Literature
dotLab® mX
dotLab Brochures
Application Briefs
- Antibody Isotype Determination (Application Brief) [PDF]
- Detection of E. coli Bacteria by Diffractive Optics (Application Brief) [PDF]
- Detection of Protein Complexes (Application Brief) [PDF]
- Development of a Multiplex Biomarker Assay (Application Brief) [PDF]
- Development of Rapid and Sensitive Serological Assays (Application Brief) [PDF]
- Extended Dynamic Range during Multiplex Analysis (Application Brief) [PDF]
- Extended Dynamic Range on Multiplex panelPlus® Sensors (Application Brief) [PDF]
- Influenza Virus Detection on Nasal Swab Samples (Application Brief) [PDF]
- Picomolar Level Biomarker Detection in Complex Media Using an Indirect Sandwich Assay (Application Brief) [PDF]
- Protein Detection and Quantitation by Diffraction-based Immunoassay (Application Brief) [PDF]
- Quantitative Assay for Rapid NSE Detection (Application Brief) [PDF]
- Rapid Determination of IgG Titer and Avidity (Application Brief) [PDF]
- Rapid Development and Optimization of Immunoassays by Diffractive Optics (Application Brief) [PDF]
Whitepapers
- Comparison of antiserum titers (Whitepaper) [PDF]
- Development of a novel diffraction based immunoassay for characterizing the primary and ternary structure of the circulating form of cardiac troponin (whitepaper) [PDF]
- Development of a Rapid Serological Assay for Strongyloides Infection Using Diffraction-Based Optical Biosensors (Whitepaper) [PDF]
- Rapid and Improved Immunoassay Development and Optimization Using the dotLab® mX System (whitepaper) [PDF]
- Rapid Conversion of NSE ELISA to Diffraction Based Immunoassay (Whitepaper) [PDF]
- Rapid Determination of IgG Titer and Avidity Using Optical Diffraction (Whitepaper) [PDF]
- Versatile and Customizable Multiplexed Assays Using Optical Diffraction (Whitepaper) [PDF]
Research Articles
- A Novel Approach to Label-Free Sensing: Diffractive Optics Technology (dot®) – JF Houle, Comb Chem High High Throughput Screening, (2009), 12, 801-811. Access required
- Development of a Qualitative Sequential Immunoassay for Characterizing the Intrinsic Properties of Circulating Cardiac Troponin I – Yixin Lin, Qin Fu, Jie Zhu, Julie M. Miller, and Jennifer E. Van Eyk. Journal of Clinical Chemistry. 2010 May 28; 56(8):1307-1319. doi:10.1373/clinchem.2009.135186.
- Diffractive Optics Technology: A Novel Detection Technology for Immunoassays (Clinical Chemistry 52 (11), 2006, page 2168) [PDF]
- Label-free and amplified quantitation of proteins in complex mixtures using diffractive optics technology – S. Cleverly, I. Chen, J-F Houle, J. Chromatography B, 878 (2010) 264-270 (journal access required)
- Solving the multiplexing-dynamic range conundrum with Diffractive Optics Technology (dot™); Nature An Nature Methods, January 2007 (article) [PDF]
Ziplex Automated Workstation
Brochures
- Breast Cancer Xpress Chips Product Information [PDF]
- Colon Cancer Xpress Chips Product Information [PDF]
- Inflammation Xpress Chips Product Information [PDF]
- Metabolic Xpress Chips Product Information [PDF]
- Ziplex System Brochure [PDF]
Research Articles
- The chemiluminescence based Ziplex® automated workstation focus array reproduces ovarian cancer Affymetrix GeneChip® expression profiles – Michael CJ Quinn, Daniel J Wilson, Fiona Young, Adam A Dempsey, Suzanna L Arcand, Ashley H Birch, Paulina M Wojnarowicz, Diane Provencher, Anne-Marie Mes-Masson, David Englert, Patricia N Tonin, Journal of Translational Medicine 2009, 7:55 (6 July 2009)
- Transcriptional dysregulation in NIPBL and cohesin mutant human cells. – Jinglan Liu, Zhe Zhang, Masashige Bando, Takehiko Itoh, Matthew A. Deardorff, Dinah Clark, Maninder Kaur, Stephany Tandy, Tatsuro Kondoh, Eric Rappaport, Nancy B. Spinner, Hugo Vega, Laird G. Jackson, Katsuhiko Shirahige, and Ian D. Krantz. PLoS Biology. 2009 May 26;7(5):e1000119. doi:10.1371/journal.pbio.1000119.
- Use of the DNA Flow-Thru Chip, a Three-Dimensional BioChip, for Typing and Subtyping of Influenza Viruses – Nicole Kessler, Olivier Ferraris, Kevin Palmer, Wayne Marsh and Adam Steel. Journal of Clinical Microbiology, May 2004, p.2173-2185
Application Notes and Whitepapers
- Biomarker Translation from Global Expression Arrays to Focused Arrays (Application Brief) [PDF]
- Biomarker Translation from Global Expression Arrays to Focused Arrays on the Ziplex System (Application Note) [PDF]
- Gene Expression Profiling on the Ziplex® System Demonstrates High Inter-platform Concordance (Whitepaper) [PDF]
- Proteomic TipChip for High Speed Serology (Application Brief) [PDF]
- Ziplex System & Proteomic TipChip for High Speed Serodiagnostics of Infectious Disease (Application Note) [PDF]
Posters
- A 43-gene gene expression array for profiling of clinical samples in the development and validation of a breast cancer recurrence test [PDF]
- Amplification of mRNA without 3’ bias from formalin-fixed paraffin-embedded (FFPE) breast cancer tissues and multiplex expression analysis on flow-through microarrays [PDF]
- Identifying a Diagnostic Classifier of CdLS by a Step-wise Multi-platform Procedure (Poster) [PDF]
- New Technologies for FFPE Samples: Improved RNA Isolation and novel cDNA priming for qPCR and for universal mRNA amplification [PDF]
- System Verification of Ziplex®, a multiplex gene expression system for translational research and clinical diagnostics [PDF]
- Ziplex System & Proteomic TipChip for High Speed Serodiagnosis of Infectious Disease (Poster) [PDF]